I study the behavioral and neural mechanisms underlying affective learning and experience, with a focus on the role of
neuromodulatory systems (dopamine, norepinephrine, opioids) and interactions between top-down and bottom-up processes. My
current research questions are: What is the neuromodulatory basis of pain-avoidance learning? How do prior expectations shape the perception of affective events? And how do expectations interact with experience-based learning? I address these questions using
behavioral and psychophysiological measures, neuroimaging (fMRI, EEG), pharmacological manipulations, and computational modeling.


I studied cognitive psychology at the University of Groningen, the Netherlands, and cognitive neuroscience at the University of York, UK. In 2011, I obtained my PhD at Leiden University, the
Netherlands, on a thesis titled “Arousal, exploration and the locus coeruleus-norepinephrine system”. I then spent 3.5 postdoctoral years at the University of Colorado Boulder, USA, where I studied the behavioral and neural mechanisms of pain-related learning and decision making. In January 2015 I returned to Leiden University with a VENI grant.

Click here to see my CV.

Professional website of Marieke Jepma